Best quality Advanced Drug Coating and Controlled Release Agent

Short Description:

Product Name: Hydroxypropyl Methyl Cellulose
Synonyms: HPMC;MHPC;hydroxylpropylmethylcellulose;Hydroxymethylpropylcellulose;methocel E,F,K;HydroxypropylMethylCellulose(Hpmc)
CAS: 9004-65-3
Molecular Formula:C3H7O*
Formula Weight:59.08708
Appearance:: White Powder
Raw material : Refined cotton
EINECS: 618-389-6
Trademark: QualiCell
Origin : China
MOQ: 1ton


Product Detail

Product Tags

We keep on with our business spirit of “Quality, Performance, Innovation and Integrity”. We goal to create much more worth for our customers with our rich resources, state-of-the-art machinery, experienced workers and exceptional providers for Best quality Advanced Drug Coating and Controlled Release Agent, Created goods with brand benefit. We attend seriously to produce and behave with integrity, and with the favor of clients at home and overseas from the xxx industry.
We keep on with our business spirit of “Quality, Performance, Innovation and Integrity”. We goal to create much more worth for our customers with our rich resources, state-of-the-art machinery, experienced workers and exceptional providers for Pharmacoat HPMC, During the short years, we serve our clients honestly as Quality First, Integrity Prime, Delivery Timely, which has earned us an outstanding reputation and an impressive client care portfolio. Looking forward to working with you Now!

Product Description

Hydroxypropyl Methyl Cellulose(HPMC)

Molecular Formula
Hypromellose (Hydroxypropylmethylcellulose: HPMC) substitution type 2910, 2906, 2208 (USP)
Physical Properties
- White or yellowish white powder
- Soluble in mixed organic or aqueous solvent
- Making up transparent film when solvent remove
- No chemical reaction with drug due to its non-ionic property
- Molecular Weight : 10,000 ~ 1,000,000
- Gel point : 40 ~ 90℃
- Auto-ignition Point : 360℃

Hydroxypropyl Methylcellulose (HPMC) Pharmaceutical Grade is Hypromellose pharmaceutical excipient and supplement,which can be used as thickener, dispersant, emulsifier and film-forming agent.

QualiCell Cellulose ether consists of methyl cellulose (USP, EP,BP,CP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, EP,BP,CP) each available in several grades differing in viscosity.HPMC products are derived from natural refined cotton linter and wood pulp, meeting all the requirements of the USP, EP, BP, along with Kosher and Halal Certifications.

In the manufacturing process, highly purified natural cotton is etherified with methyl chloride or with the combination of methyl chloride and propylene oxide to form a water-soluble, non-ionic cellulose ether. No animal resources are used in the production of HPMC.HPMC can be used as a binder for solid dosage forms such as tablets and granules. It also serves a variety of functions, for examples, in enhancing water retention, thickening, acting as a protective colloid due to its surface activity, sustaining release, and film formation.

QualiCell HPMC provides a variety of functions such as water retention, protective colloid, surface activity, sustained release. It is a non-ionic compound resistant to salting out and stable over a wide pH-range. Typical applications of HPMC are binder for solid dosage forms such as tablets and granules or thickener for liquid applications.

Pharma HPMC comes in diverse viscosity ranges from 3 to 200,000 cps, and it can be widely used for tablet coating, granulation, binder, thickener, stabilizer and making vegetable HPMC capsule.

Chemical Specification

Hypromellose

Specification

60E( 2910 ) 65F( 2906 ) 75K( 2208 )
Gel temperature (℃) 58-64 62-68 70-90
Methoxy (WT%) 28.0-30.0 27.0-30.0 19.0-24.0
Hydroxypropoxy (WT%) 7.0-12.0 4.0-7.5 4.0-12.0
Viscosity(cps, 2% Solution) 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000

Product Grade

Hypromellose

Specification

60E( 2910 ) 65F( 2906 ) 75K( 2208 )
Gel temperature (℃) 58-64 62-68 70-90
Methoxy (WT%) 28.0-30.0 27.0-30.0 19.0-24.0
Hydroxypropoxy (WT%) 7.0-12.0 4.0-7.5 4.0-12.0
Viscosity(cps, 2% Solution) 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000

Application

Pharma Grade HPMC enable the production of controlled-release formulations with the convenience of the most widely used tablet-binding mechanism. Pharma Grade offer good powder flow, content uniformity, and compressibility, making them well suited for direct compression.

Pharma Excipients Application Pharma Grade HPMC Dosage
Bulk Laxative 75K4000,75K100000 3-30%
Creams, Gels 60E4000,75K4000 1-5%
Ophthalmic Preparation 60E4000 01.-0.5%
Eye Drops Preparations 60E4000 0.1-0.5%
Suspending Agent 60E4000, 75K4000 1-2%
Antacids 60E4000, 75K4000 1-2%
Tablets Binder 60E5, 60E15 0.5-5%
Convention Wet Granulation 60E5, 60E15 2-6%
Tablet Coatings 60E5, 60E15 0.5-5%
Controlled Release Matrix 75K100000,75K15000 20-55%

Features and Benefits

- Improves product flow characteristics
- Reduces processing times
- Identical, stable dissolution profiles
- Improves content uniformity
- Reduces production costs
- Retains tensile strength after double compaction (roller compaction) process

Packaging

The standard packing is 25kg/drum
20’FCL: 9 ton with palletized; 10 ton unpalletized.
40’FCL: 18 ton with palletized; 20 ton unpalletized.We keep on with our business spirit of “Quality, Performance, Innovation and Integrity”. We goal to create much more worth for our customers with our rich resources, state-of-the-art machinery, experienced workers and exceptional providers for Best quality Advanced Drug Coating and Controlled Release Agent, Created goods with brand benefit. We attend seriously to produce and behave with integrity, and with the favor of clients at home and overseas from the xxx industry.
Best quality Pharmacoat HPMC, During the short years, we serve our clients honestly as Quality First, Integrity Prime, Delivery Timely, which has earned us an outstanding reputation and an impressive client care portfolio. Looking forward to working with you Now!


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