China Factory for High Viscosity Cellulose Ether Hydroxypropyl Methyl Cellulose HPMC
We continuously execute our spirit of ”Innovation bringing development, Highly-quality ensuring subsistence, Management advertising and marketing gain, Credit history attracting buyers for China Factory for High Viscosity Cellulose Ether Hydroxypropyl Methyl Cellulose HPMC, Welcomes all overseas friends and merchants to establish collaboration with us. We will provide you with honest, high quality and efficient service to meet your requirements.
We continuously execute our spirit of ”Innovation bringing development, Highly-quality ensuring subsistence, Management advertising and marketing gain, Credit history attracting buyers for China Hydroxypropyl Methyl Cellulose and HPMC, Our factory covers an area of 12,000 square meters, and has a staff of 200 people, among which there are 5 technical executives. We have been specialized in producing.Now we have rich experience in export. Welcome to contact us and your enquiry will likely be replied as soon as possible.
Product Description
Hydroxypropyl Methyl Cellulose(HPMC)
Molecular Formula
Hypromellose (Hydroxypropylmethylcellulose: HPMC) substitution type 2910, 2906, 2208 (USP)
Physical Properties
- White or yellowish white powder
- Soluble in mixed organic or aqueous solvent
- Making up transparent film when solvent remove
- No chemical reaction with drug due to its non-ionic property
- Molecular Weight : 10,000 ~ 1,000,000
- Gel point : 40 ~ 90℃
- Auto-ignition Point : 360℃
Hydroxypropyl Methylcellulose (HPMC) Pharmaceutical Grade is Hypromellose pharmaceutical excipient and supplement,which can be used as thickener, dispersant, emulsifier and film-forming agent.
QualiCell Cellulose ether consists of methyl cellulose (USP, EP,BP,CP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, EP,BP,CP) each available in several grades differing in viscosity.HPMC products are derived from natural refined cotton linter and wood pulp, meeting all the requirements of the USP, EP, BP, along with Kosher and Halal Certifications.
In the manufacturing process, highly purified natural cotton is etherified with methyl chloride or with the combination of methyl chloride and propylene oxide to form a water-soluble, non-ionic cellulose ether. No animal resources are used in the production of HPMC.HPMC can be used as a binder for solid dosage forms such as tablets and granules. It also serves a variety of functions, for examples, in enhancing water retention, thickening, acting as a protective colloid due to its surface activity, sustaining release, and film formation.
QualiCell HPMC provides a variety of functions such as water retention, protective colloid, surface activity, sustained release. It is a non-ionic compound resistant to salting out and stable over a wide pH-range. Typical applications of HPMC are binder for solid dosage forms such as tablets and granules or thickener for liquid applications.
Pharma HPMC comes in diverse viscosity ranges from 3 to 200,000 cps, and it can be widely used for tablet coating, granulation, binder, thickener, stabilizer and making vegetable HPMC capsule.
Chemical Specification
Hypromellose Specification |
60E( 2910 ) | 65F( 2906 ) | 75K( 2208 ) |
Gel temperature (℃) | 58-64 | 62-68 | 70-90 |
Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
Viscosity(cps, 2% Solution) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 |
Product Grade
Hypromellose Specification |
60E( 2910 ) | 65F( 2906 ) | 75K( 2208 ) |
Gel temperature (℃) | 58-64 | 62-68 | 70-90 |
Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
Viscosity(cps, 2% Solution) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 |
Application
Pharma Grade HPMC enable the production of controlled-release formulations with the convenience of the most widely used tablet-binding mechanism. Pharma Grade offer good powder flow, content uniformity, and compressibility, making them well suited for direct compression.
Pharma Excipients Application | Pharma Grade HPMC | Dosage |
Bulk Laxative | 75K4000,75K100000 | 3-30% |
Creams, Gels | 60E4000,75K4000 | 1-5% |
Ophthalmic Preparation | 60E4000 | 01.-0.5% |
Eye Drops Preparations | 60E4000 | 0.1-0.5% |
Suspending Agent | 60E4000, 75K4000 | 1-2% |
Antacids | 60E4000, 75K4000 | 1-2% |
Tablets Binder | 60E5, 60E15 | 0.5-5% |
Convention Wet Granulation | 60E5, 60E15 | 2-6% |
Tablet Coatings | 60E5, 60E15 | 0.5-5% |
Controlled Release Matrix | 75K100000,75K15000 | 20-55% |
Features and Benefits
- Improves product flow characteristics
- Reduces processing times
- Identical, stable dissolution profiles
- Improves content uniformity
- Reduces production costs
- Retains tensile strength after double compaction (roller compaction) process
Packaging
The standard packing is 25kg/drum
20’FCL: 9 ton with palletized; 10 ton unpalletized.
40’FCL: 18 ton with palletized; 20 ton unpalletized.We continuously execute our spirit of ”Innovation bringing development, Highly-quality ensuring subsistence, Management advertising and marketing gain, Credit history attracting buyers for China Factory for High Viscosity Cellulose Ether Hydroxypropyl Methyl Cellulose HPMC, Welcomes all overseas friends and merchants to establish collaboration with us. We will provide you with honest, high quality and efficient service to meet your requirements.
China Factory for China Hydroxypropyl Methyl Cellulose and HPMC, Our factory covers an area of 12,000 square meters, and has a staff of 200 people, among which there are 5 technical executives. We have been specialized in producing.Now we have rich experience in export. Welcome to contact us and your enquiry will likely be replied as soon as possible.