OEM/ODM China hydroxypropyl methylcellulose uses in tablets - Pharmaceutical Grade Hydroxypropyl Methylcellulose(HPMC) – Anxin

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OEM/ODM China hydroxypropyl methylcellulose uses in tablets - Pharmaceutical Grade Hydroxypropyl Methylcellulose(HPMC) – Anxin Detail:

Product Description

CAS NO.:9004-65-3

Molecular Formula
Hypromellose (Hydroxypropylmethylcellulose: HPMC) substitution type 2910, 2906, 2208 (USP)
Physical Properties
- White or yellowish white powder
- Soluble in mixed organic or aqueous solvent
- Making up transparent film when solvent remove
- No chemical reaction with drug due to its non-ionic property
- Molecular Weight : 10,000 ~ 1,000,000
- Gel point : 40 ~ 90℃
- Auto-ignition Point : 360℃

Hydroxypropyl Methylcellulose (HPMC) Pharmaceutical Grade is Hypromellose pharmaceutical excipient and supplement,which can be used as thickener, dispersant, emulsifier and film-forming agent.

KimaCell Cellulose ether consists of methyl cellulose (USP, EP,BP,CP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, EP,BP,CP) each available in several grades differing in viscosity.HPMC products are derived from natural refined cotton linter and wood pulp, meeting all the requirements of the USP, EP, BP, along with Kosher and Halal Certifications.

In the manufacturing process, highly purified natural cotton is etherified with methyl chloride or with the combination of methyl chloride and propylene oxide to form a water-soluble, non-ionic cellulose ether. No animal resources are used in the production of HPMC.HPMC can be used as a binder for solid dosage forms such as tablets and granules. It also serves a variety of functions, for examples, in enhancing water retention, thickening, acting as a protective colloid due to its surface activity, sustaining release, and film formation.

KimaCell HPMC provides a variety of functions such as water retention, protective colloid, surface activity, sustained release. It is a non-ionic compound resistant to salting out and stable over a wide pH-range. Typical applications of HPMC are binder for solid dosage forms such as tablets and granules or thickener for liquid applications.

Pharma HPMC comes in diverse viscosity ranges from 3 to 200,000 cps, and it can be widely used for tablet coating, granulation, binder, thickener, stabilizer and making vegetable HPMC capsule.

Chemical Specification

Hypromellose

Specification

60E

( 2910 )

65F

( 2906 )

75K

( 2208 )

Gel temperature (℃) 58-64 62-68 70-90
Methoxy (WT%) 28.0-30.0 27.0-30.0 19.0-24.0
Hydroxypropoxy (WT%) 7.0-12.0 4.0-7.5 4.0-12.0
Viscosity(cps, 2% Solution) 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000

Product Grade

Hypromellose

Specification

60E

( 2910 )

65F

( 2906 )

75K

( 2208 )

Gel temperature (℃) 58-64 62-68 70-90
Methoxy (WT%) 28.0-30.0 27.0-30.0 19.0-24.0
Hydroxypropoxy (WT%) 7.0-12.0 4.0-7.5 4.0-12.0
Viscosity(cps, 2% Solution) 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000

Application

Pharma Grade HPMC enable the production of controlled-release formulations with the convenience of the most widely used tablet-binding mechanism. Pharma Grade offer good powder flow, content uniformity, and compressibility, making them well suited for direct compression.

Pharma Excipients Application Pharma Grade HPMC Dosage
Bulk Laxative 75K4000,75K100000 3-30%
Creams, Gels 60E4000,75K4000 1-5%
Ophthalmic Preparation 60E4000 01.-0.5%
Eye Drops Preparations 60E4000 0.1-0.5%
Suspending Agent 60E4000, 75K4000 1-2%
Antacids 60E4000, 75K4000 1-2%
Tablets Binder 60E5, 60E15 0.5-5%
Convention Wet Granulation 60E5, 60E15 2-6%
Tablet Coatings 60E5, 60E15 0.5-5%
Controlled Release Matrix 75K100000,75K15000 20-55%

Features and Benefits

- Improves product flow characteristics
- Reduces processing times
- Identical, stable dissolution profiles
- Improves content uniformity
- Reduces production costs
- Retains tensile strength after double compaction (roller compaction) process

Packaging

The standard packing is 25kg/drum
20’FCL: 9 ton with palletized; 10 ton unpalletized.
40’FCL: 18 ton with palletized; 20 ton unpalletized.


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We pursue the administration tenet of "Quality is exceptional, Assistance is supreme, Reputation is first", and will sincerely create and share success with all clients for OEM/ODM China hydroxypropyl methylcellulose uses in tablets - Pharmaceutical Grade Hydroxypropyl Methylcellulose(HPMC) – Anxin, The product will supply to all over the world, such as: Paraguay, Tunisia, Ottawa, Insisting on the high quality generation line management and customers expert assistance, we now have designed our resolution to offer our buyers using the to start with amount getting and just after services practical experience. Maintaining the prevailing friendly relations with our buyers, we however innovate our solution lists all of the time to satisfy the brand new demands and adhere to the most up-to-date development of the market in Malta. We are ready to face the worries and make the improve to understand all the possibilities in international trade.
  • A nice supplier in this industry, after a detail and careful discussion, we reached a consensus agreement. Hope that we cooperate smoothly.
    5 Stars By Daisy from venezuela - 2018.09.16 11:31
    Sales manager is very enthusiastic and professional, gave us a great concessions and product quality is very good,thank you very much!
    5 Stars By Johnny from Romania - 2017.03.08 14:45

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